Tranexamic Acid (Topical)
- Effective dose
- 2–5 %
- Evidence
- 3/5· Moderate
Last updated June 1, 2026
What it is
Tranexamic acid is a topical active best known for treating melasma and stubborn discoloration. It interrupts the signaling between skin cells and pigment-producing melanocytes, which lowers excess melanin production and helps calm pigment driven by inflammation and UV exposure. This makes it useful for both melasma and post-inflammatory hyperpigmentation.
Benefits
Topical tranexamic acid reduces melasma severity over roughly 12 weeks, with trials of 3% and 5% formulations showing efficacy comparable to treatments like glycolic acid peels or hydroquinone but with a better tolerability profile. Studies point to an effective range of about 2-5%, and it is frequently combined with other brighteners. It also helps fade redness and discoloration left behind by acne.
When to take it
Can be used once or twice daily on clean skin; consistent use over several weeks is needed to see fading. Pair with daily sunscreen, which is critical for any melasma treatment.
Side effects
Mild irritation, redness, or dryness can occur but are generally uncommon at typical concentrations. It is considered a comparatively gentle option among pigment treatments.
Sources
Products containing Tranexamic Acid (Topical)
No products in our database contain this ingredient yet.