Squalane
- Effective dose
- 1–100 %
- Evidence
- 3/5· Moderate
Last updated June 1, 2026
What it is
Squalane is a lightweight emollient and a stable, hydrogenated form of squalene, a lipid the skin naturally produces in sebum. Applied topically, it softens the skin surface and helps the barrier hold onto moisture by reinforcing the lipid layer between skin cells. It is valued as a non-greasy moisturizing base rather than as an active that targets a specific concern.
Benefits
Squalane improves skin softness and supports hydration, making it useful for dry, eczema-prone, and easily irritated skin, and laboratory work suggests it may help protect dermal fibroblasts from UV-related collagen suppression. Formulations typically use it anywhere from roughly 1% for light hydration up to 100% in pure facial oils. Its emollient action complements humectants and barrier lipids in a layered routine.
When to take it
Can be used morning or night, applied near the end of a routine to seal in lighter products. A few drops are enough for the whole face.
Side effects
Squalane is non-comedogenic for most users and is non-irritating even at full strength. Adverse reactions are rare and usually mild.
Sources
Products containing Squalane
No products in our database contain this ingredient yet.