Retinol
- Effective dose
- 0.025–1 %
- Evidence
- 5/5· Robust
Last updated June 1, 2026
What it is
Retinol is a vitamin A derivative that converts to retinoic acid in the skin. Retinoic acid binds nuclear receptors that regulate keratinocyte differentiation and collagen synthesis.
Benefits
Reduces fine lines, evens tone, and improves overall skin texture with consistent use over 12+ weeks. Stronger evidence than most other skincare actives.
When to take it
Apply at night, as retinoids degrade in light, and always pair with broad-spectrum SPF in the morning. Start 2-3 nights per week and build up frequency as tolerance develops.
Side effects
Irritation, peeling, and increased sun sensitivity, especially when starting. Build tolerance gradually and pair with daily SPF.
Sources
Products containing Retinol
No products in our database contain this ingredient yet.