Retinaldehyde
- Effective dose
- 0.05–0.1 %
- Evidence
- 4/5· Strong
Last updated June 1, 2026
What it is
Retinaldehyde (retinal) is a vitamin A derivative and one of the most potent non-prescription retinoids. It sits just one conversion step from active retinoic acid in the skin, so it acts faster than retinol while typically irritating less than prescription tretinoin.
Benefits
Improves wrinkles, skin texture, and signs of photoaging while supporting epidermal thickness and elasticity; clinical studies use creams in the 0.05-0.1% range, with 0.05% shown to increase epidermal thickness and elasticity.
When to take it
Apply at night to clean, dry skin, starting a few times per week and building tolerance; always pair with broad-spectrum SPF in the morning.
Side effects
Can cause dryness, redness, and mild peeling, though typically less than prescription retinoids at comparable strength. It increases sun sensitivity.
Sources
Products containing Retinaldehyde
No products in our database contain this ingredient yet.