Skincare

Mandelic Acid

Effective dose
5–10 %
Evidence
3/5· Moderate

Last updated June 1, 2026

What it is

Mandelic acid is an alpha hydroxy acid derived from bitter almonds with a relatively large molecule. Its size slows penetration into the skin, so it exfoliates dead surface cells and helps regulate keratinization more gradually than smaller AHAs, which tends to make it better tolerated on sensitive skin.

Benefits

Improves acne, uneven texture, and post-acne hyperpigmentation; leave-on products typically use about 5-10%, while in-office peels are studied at much higher strengths (around 30-45%).

When to take it

Best applied at night, with broad-spectrum SPF the next morning because AHAs raise UV sensitivity. Introduce slowly and increase frequency as the skin adjusts.

Side effects

May cause mild stinging, dryness, or redness, though irritation and post-inflammatory hyperpigmentation tend to be lower than with stronger AHAs. As an AHA, it increases sun sensitivity.

Sources

Products containing Mandelic Acid

No products in our database contain this ingredient yet.