Copper Peptides (GHK-Cu)
- Effective dose
- 0.05–3 %
- Evidence
- 3/5· Moderate
Last updated June 1, 2026
What it is
GHK-Cu is a tripeptide bound to a copper ion. It is involved in wound healing and signals fibroblasts to upregulate collagen and elastin production.
Benefits
Improvements in firmness and texture in small clinical trials. Evidence is promising but the body of research is smaller than for retinoids.
When to take it
Typically used once or twice daily on clean skin before heavier creams; some users reserve it for the evening and apply vitamin C in the morning to keep the actives separate. Consistency over several weeks is needed for visible firming.
Side effects
Possible irritation. Stability in formulation matters; copper peptides can be deactivated when combined with vitamin C or strong acids in the same product.
Sources
Products containing Copper Peptides (GHK-Cu)
No products in our database contain this ingredient yet.